Equipment
The versatility of
our 700 Series is exhibited by the wide range of chest sizes available:
3.0, 6.7, 12.7, 17.0, and 20.0 cu. ft. (84.9, 189.7, 359.6, 481.4, and
566.3 liters). These units are manufactured to provide ultra-low
temperatures for long-term storage of your samples. Stress tested to
operate efficiently at a temperature range of -50C to -86C (-58F to
-123F), these reliable units are designed for basic, everyday use. They
are Reliable Long Term Storage. Freezers feature a durable, powder
coated galvannealed interior. Sub-lid(s) are included to reduce cold
air loss and aid in temperature recovery after lid closings.
Conveniently located information center with programmable controls,
temperature display, and an optional chart recorder or datalogger
allows continuous monitoring. Microprocessor controller maintains a
constant temperature that can be set in one degree C increments.
Set points below the freezer's operating range are prohibited.
The Plas-Labs anaerobic chamber is a
Bio-Containment level 3 closed loop containment system. The Closed-Loop
Containment Isolator is a completely automated negative pressure glove
box. The system is engineered and programmed to maintain a slight
negative
working pressure ( -0.50 in H2O ). The internal atmosphere is
continually filtered by two HEPA filters. Filters are rated at 99.9997%
efficiency. These isolation units may be coupled together for multiple
station work
processes. They are large enough for four (4) sets of glove ports
(operators).
Developed from a unique combination of
ingenuity and high-level
technical resources, the Cell Lab Quanta SC is a flow cytometry system
that simultaneously measures electronic volume, side scatter
and;three
fluorescent colors to provide unsurpassed population resolution and
accurate cell counting. This advanced flow cytometer has multiple
excitation wavelengths, including 488 nm laser and a UV light source
optimized for excitation at 366, 405, 435 nm. Together with
interchangeable filters, the Quanta SC allows flexible fluorochrome
selection for a variety of multicolor applications typically only
achievable with expensive and complicated systems. Side scatter and
Coulter volume make size analysis and fluorescent measurements more
precise. Unique user features expand ease-of-use and flexibility. When
all the details are added together, the sum is performance.
The Barnstead MaxQ 4000 series A-Class shaker allows
the user to control temperature by a Proportional / Integral /
Derivative
microprocessor-based controller. Solid-state control maintains time and
speed and is adjustable with rotary dials. Analog tachometer displays
speed in RPM, verifying accuracy of speed setting. Refrigerated units
feature environmentally safe CFC free insulation and coolant. It has
Space Efficient Tubular Heaters.; Drive Interrupt Halts Shaking
Action When Lid is Opened. All Set Points are Retained by Non-Volatile
Memory that Automatically Reactivates After Power is Restored. Visual,
User Adjustable Over-Temperature Safety Signal with Independent
Thermostat Controls the Heat if Main Controller Fails.; It
features a 50 lb (22.7 kg) Platform Load Capacity at Safe Speeds Less
Than 400
rpm.; It is also UL, cUL and CE Certified.
The Model 1575 Immuno-wash "Microplate" Washer
is
flexible, compact and dependable. A wide choice of washing methods can
be combined in complex washing sequences to meet the toughest technical
demands. Integrated vacuum and dispensing pumps ensure accurate and
quiet washing. It features easy wash protocol creation and storage (75
user-defined protocols can be stored in memory). It adapts to strip or
plate wash modes with interchangeable manifolds for 8- and 12-well
strips.; Its protocols are flexible - the user decides the soak
time and number of wash cycles. Compatibility with flat, U- or V-bottom
plates makes for an easy to use machine. Programmable needle positions
for bottom washing, crosswise aspiration and overflow washing mean you
have ultimate flexibility. One-half height and power wash cycles are
also available. Dispense speed control and plate-shaking options make
it easy to adapt existing protocols .
Fluorescence microscopy differs from other microscopy methods in a variety of ways.; Normal brightfield microscopy in a high power microscope takes light and passes it through a thin specimen on a glass microscope slide.; Phase contrast microscopy begins with normal light, then shifts it out of phase and this phase shift is translated into a difference in viewing intensity.; Darkfield microscopy is an illumination technique where the biological specimen is illuminated from the sides instead of from the bottom.
Fluorescence microscopy differs from all these techniques in that the visible light in the microscope eyepieces is not the original light emitted by the light source.; The light you see is actually light that has fluoresced from the fluorescing microscope specimen.; A high intensity light source is used.; This light is passed through an dichroic filter cube containing a fluorescence bandpass excitation filter.; Only specific wavelengths of light are allowed to pass and reach the fluorescence specimen.; After the incident filtered light reaches the specimen, it is no longer used, and any amount reflecting back into the microscope objective to the dichroic filter is filtered out by the emission filter.; The specimen fluoresces and it is this fluorescing light that passes back through the fluorescence emission filter and goes to the microscope eyepieces to provide a fluorescence image of the specimen.
For the professional, student, or faculty
researcher, the new 4300 DNA Analysis System from LI-COR will
accelerate your research and improve the quality of your data. High
confidence in more precise data is the edge that researchers using
LI-COR DNA analysis systems have had for more than 10 years. The 4300
System is a third generation instrument based on LI-COR's highly
sensitive infrared fluorescence detection technology. 4300
instrumentation, software, reagents, and applications are all part of
an integrated system designed to achieve the highest accuracy. Infrared
detection is a key advantage since biological contaminants, gels, and
glass plates have little infrared fluorescence. With low background
fluorescence, dye fluorescence signals are clean and strong. Infrared
detection gives 4300 Systems excellent sensitivity. As samples pass in
front of the scanning laser/microscope, two solid-state avalanche
photo diodes detect fluorescence. Optical filtering assures that each
detector measures fluorescence from only one of the infrared dyes. The
4300 instrument contains a server that can operate either in a
stand-alone configuration or connected to your network. An Internet
browser or LI-COR Application Software can be used to start
electrophoresis. The server software completely controls
electrophoresis and data storage during a run. Two 16-bit TIFF images
are stored on the 4300's server during a run. The 4300 System gives you
maximum data access. Any computer can connect to the 4300 System via
Internet browser or LI-COR Application Software (e-Seq, Saga, etc.). In
a network environment, image data can be accessed from your office or
over the Internet. Secure, password-protected server software assures
that only members of your project have access to your data.
Standard with 8-cores: Two 2.8GHz, 3.0GHz, or 3.2GHz
Quad-Core Intel Xeon 5400 series processors.; They all have Eight
FB-DIMM slots on two memory riser cards (four slots per card)
supporting up to 32GB of main memory.; These computers allow us to
interpret any data we have, in a fast and easy manner.; The 20
inch apple display makes viewing even the biggest pictures a
breeze.; With programs such as Word, Excel, PowerPoint, Adobe
Reader, and Adobe Dream weaver we have something for everyone.;
This makes a great place to do homework, or register for classes.;
Combined with the Mac Server this is a powerful lab for anyone to use.
Building on the worldwide success of the
OmniGrid® Micro arrayer, the Omnigrid® Accent offers a high-performance
benchtop solution for printing quality arrays. The Accent arrays
biological samples from 3 plates onto a 50-slide platform and supports
a print head with up to 48 pins.The whisper-quiet operation and
superior printing precision of this high-speed arrayer is the result of
state-of-the-art engineering. The transparent enclosure with
positive-pressure HEPA filtering provides a dust-free printing
environment.; The OmniGrid® Accent utilizes the same user-friendly
interface as the popular OmniGrid® and the OmniGrid® 300 giving users
maximum flexibility over the printing process. The software package
offers extensive control over array design, pin configuration, cleaning
protocols and sample sequences. The sample tracking feature seamlessly
integrates OmniGrid® Accent's array data with leading scanner and
analysis software.
The Eppendorf Personal Microcentrifuges
MiniSpin and MiniSpin plus are compact and easy to use, and they are
powerful enough so that each workstation can be equipped with a
"personal" centrifuge for a wide range of molecular biology separations
and quick spins. Two models are available to meet your performance
requirements.; The Mini Spin Plus Microcentrifuges you will find
in most our labs will spin at 14500 rpm or 14000 x gravity.; They
have the ability to spin from 15 seconds to 99 minutes with continuous
functions, as well as a short spin button for shorter manual
spins.
Information Coming Soon, for more information Email Dr. Gallo.
The patch clamp technique was introduced to
biology initially by Cole in the late 1930's and was exploited by the
Hodgkin & Huxley team in the late 1940's. The Hodgkin & Huxley
conceptual model of the axon presented in 1952 was based on data
acquired using this technique. Unfortunately, neither group presented a
model of the complete neuron that supported their proposals. The
technique has been applied widely since their time using a variety of
modifications. All of these activities have been exploratory in nature.
They have seldom included a theoretical model that they were attempting
to confirm. The normal approach has been to attempt to extract a model,
after the fact, from the data. Dr. William Cliff
can tell you more if you are interested in what we do with this system.
The Fluor-S MAX MultiImager is
a quantitative imaging system for capturing digital data from single
and multi-color fluorescence, chemiluminescence, chemifluorescence and
coloimetric samples. Using super-cooled CCD technology in combination
with a unique ultraviolet illumination mechanism and high efficiency,
the Fluor- S MAX offers high sensitivity, uniformity, flexibility and
dynamic range for the analysis of electrophoretic samples. The Personal
Molecular Imager FX system is the most flexible isotope imaging system
available, offering radio isotopic imaging using your choice of
phosphor
screen. The Personal Molecular Imager accommodates both large (35 x 43
cm) and small (20 x 25 cm) storage phosphor screens. 
The iCycler thermal cycler offers excellent thermal
performance, fast ramping, intuitive programming, a choice of reaction
modules with different assay formats, and optional upgrades for
real-time PCR (which are available in our labs). Many user-friendly
features, including help screens and reference lists, guide you through
experiments. The high-resolution graphical interface simplifies file
and protocol management and allows printing of a variety of reports.
Standard gel electrophoresis techniques for
separation of DNA molecules provided huge advantages for molecular
biology research. However, many limitations existed with the standard
protocol in that it was unable to separate very large molecules of DNA
effectively. DNA molecules larger than 15-20kb migrating through a gel
will essentially move together in a size-independent manner. At
Columbia University in 1984, Schwartz and Cantor developed a variation
on the standard protocol by introducing an alternating voltage gradient
to better the resolution of larger molecules. This technique became
known as Pulsed Field Gel Electrophoresis (PFGE). The development of
PFGE expanded the range of resolution for DNA fragments by as much as 2
orders of magnitude.
The
current model LS 6500 (and LS6000 for that
matter) Scintillation Counter offers unparalleled flexibility in
a single high performance system, without the need of a dedicated
external computer. Advanced electronic
components, such as a Motorola 68000 Series microprocessor supported by
a digital signal processor, maximize technological lifetime and make
the LS 6500 fast and efficient. Additional functionality for the 6500 include
improved counting efficiency of dry scintillant (eg ReadyCaps); a
reversible belt carrier system that allows for more convenient
recounting of samples; counting single racks without command card
(under interrupt in the Multi Task menu), single photon counting, and
dual label studies.
Tuttnauer®/Brinkmann Bench top Autoclaves offer
fast, safe, dependable and convenient steam sterilization. Applications
include sterilization of liquids, media, instruments, glassware,
clothing and waste. Models are available with 7-, 9-, 10-, 12- or
15-inch diameter chambers. The self-contained design with refillable
reservoir controls water purity for sterilization. All models feature a
ASME-stamped, 316L stainless steel chamber with a safe and durable
design. Temperature selection is from 100°C to 134°C. Exhaust is
adjustable for sterilization of solids and liquids and a drying cycle
removes residual moisture after sterilization. Heat-insulated,
double-locking door protects against accidental burns; door cannot be
opened while chamber is under pressure and over-temperature cutoff and
over-pressure valve ensures safe operation. Analog controls and gauges
are designed for simple operation. All models use UL and CSA-approved
parts and are backed by a two-year warranty.
A spectrophotometer is a photometer
(a device for measuring light intensity) that can measure intensity as
a function of the color, or more specifically, the wavelength of light.
Perhaps the most common application of spectrophotometers is the
measurement of light absorption, but they can be designed to measure
diffuse or specular reflectance.
The Forma Scientific Sterile Work Hoods equipped
in almost every lab means we have a sterile environment to keep samples
as sterile as possible.; From pouring culture media, to growing
cells, the sterile hoods produce the perfect environment for all lab
needs.
This state-of-the-art
ultracentrifuge is able to reliably serve your lab for as long as
you'll be there. Beckman's' unsurpassed Optima series technology
includes a vacuum encased induction drive- the first of its kind in the
world. The refrigeration system is thermoelectric.; Hi tech means
no CFC's.; The vacuum system is moisture purging and thereby
drastically reduces maintenance. Featuring Microprocessor control, High
torque direct drive induction motor, and Very smooth acceleration /
deceleration profiles.; This means your samples are safe!
The VersaDoc Model 4000 imaging
system is used to capture digital images from single- and multicolor
fluorescence, chemiluminescence, chemifluorescence, and colorimetric
samples. The system uses a back-illuminated, high-sensitivity with
micro lens technology CCD detector and flat fielding technology and
includes a 50 mm and 20-40 mm zoom lens, sample tray, cleaning kit,
Quantity One software for PC, and instructions. Dimensions are 58 x 66
x 99 cm. The 4 illumination modes, epi-white & UV, trans-white
& UV (302, 254, and 365 nm) The Model 4000 is the ideal proteomics
imager, offering great flexibility (image chemiluminescent western
blots, SYPRO Ruby-stained 2-D gels and Coomassie Blue-stained 1-D gels)
and state-of-the-art CCD resolution (3.2-megapixel). The megapixel
camera provides a maximum resolution of approximately 50 nm. Some of
the camera specs are front-illuminated, high-sensitivity CCD with
micro lens technology, full-Frame CCD utilizes its entire surface to
collect light, 3.2-megapixel (2,184 x 1,472 pixel array), 12-bit, >3
orders of magnitude dynamic range, Peltier cooled.
Easy to use system offers an all in one compact
system for gel documentation of fluorescent and colorimetric samples.
Unique configuration is excellent for multiple user laboratories. A
computer is not required; though network connectivity is possible for
transfer of images directly to your computer.; New
transilluminator design supplies increased performance and efficiency.
Product enhancements include a new electronic ballast and cutting-edge
construction! Our system includes a thermal printer, which does not use
ink but instead uses heat to burn an image into a special paper,
cutting the cost of our images.; The heads up display allows for
easy focusing, and the controls are simple so minimal training is
necessary.